Short acting phenylalkylamine calcium channel blockers and...

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/277 (2006.01) A61K 31/216 (2006.01) A61P 9/00 (2006.01)

Patent

CA 2693627

The present invention relates to the use of a pharmaceutically effective amount of an short-acting calcium channel blocking compound to treat ischemic heart conditions, cardiac arrhythmias, hypertensive crisis in an emergency room setting, hypertension before, during, or after surgery, no- reflow phenomenon following reperfusion, and diseases associated with decreased skeletal muscle blood flow. The invention also relates to pharmaceutical compositions formulated for use in such methods and to kits for such methods.

La présente invention concerne l'utilisation d'une quantité efficace d'un point de vue pharmaceutique d'un composé bloquant les canaux calciques à brève durée d'action en vue du traitement des affections cardiaques ischémiques, des arythmies cardiaques, des crises d'hypertension et ce dans le cadre d'un service d'urgences, de l'hypertension, préalable, concomitante ou faisant suite à une intervention chirurgicale, du phénomène de non reperfusion faisant suite à une reperfusion et des maladies associées à une diminution de l'irrigation sanguine des muscles squelettiques. L'invention concerne également des compositions pharmaceutiques formulées en vue de leur utilisation dans le cadre desdits procédés, ainsi que des trousses permettant la mise en uvre desdits procédés.

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