Short peptides with insulin activity

Details Short peptides with insulin activity Short peptides with insulin activity

C - Chemistry, Metallurgy

07

K

C07K 7/06 (2006.01) A61K 38/04 (2006.01) A61K 38/08 (2006.01) A61K 38/28 (2006.01) C07K 5/04 (2006.01) C07K 14/62 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2058020

Short peptides with insulin activity Short peptides of the formula I X-Y-A-B-C-Cys-D-E (I) where A and B are an amino acid or a covalent bond, C and D are an amino acid or a substituted amino acid, E is a modified or unmodified amino acid or a covalent bond, X is a radical or hydrogen and Y is leucine or a covalent bond, or dimers of the peptides of the formula I with cystine as dimerization component, the stereoisomeric forms thereof where appropriate, or the physiologically tolerated salts thereof, the preparation thereof and the use thereof for the treatment of diabetes mellitus are described.

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