Shuttle vector and use in evaluation of mutation phenomenon

Details Shuttle vector and use in evaluation of mutation phenomenon Shuttle vector and use in evaluation of mutation phenomenon

C - Chemistry, Metallurgy

12

N

C12N 15/85 (2006.01) C12N 5/10 (2006.01) C12N 15/70 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2526296

La présente invention concerne une construction d'ADN, telle un vecteur navette, utile dans des méthodes de détection et/ou d'évaluation quantitative ou qualitative d'un phénomène de mutation, comme par exemple ceux intervenant au cour d'une hypermutation somatique, d'une cellule ou d'un groupe de cellules. Ce vecteur navette est également utile dans une méthode de diagnostic et/ou de pronostic d'évolution d'une maladie hématologique.

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