Sialic acid-containing glycolipid derivatives

Details Sialic acid-containing glycolipid derivatives Sialic acid-containing glycolipid derivatives

C - Chemistry, Metallurgy

07

H

C07H 15/02 (2006.01) A61K 9/127 (2006.01) A61K 31/70 (2006.01) C07H 15/04 (2006.01) C07H 15/14 (2006.01) C07H 15/18 (2006.01)

Patent

CA 2050484

- 158 - ABSTRACT Sialic acid- containing glycolipid derivatives represented by the following general formula, their production method, and the particulate carriers that contain as a constituent the sialic acid-containing glycolipid derivative(s). Image wherein ? represents the .alpha. - or the .beta.- linkage, R1, a hydrogen atom or an acetyl group, R2, a hydrogen atom, a lower alkyl group with 1 - 4 carbon atoms, an alkaline metal ion, or such, X, an oxygen or sulfur atom or a residue represented by the following formula (II) or (III), -O(CH2)mNHCO- (II) where m represents an integer from 1 to 10. -O(CH2)mCONH- (III) Y, the formula (IV). - 159 - (IV) Image wherein A represents a linear or branched chain acylamino group with 10 - 40 carbon atoms, or such B, a hydrogen atom, a carboxyl group or such, or the formula (V), and Image (V) n, an integer of 0 to 3.

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