C - Chemistry – Metallurgy – 07 – J
Patent
C - Chemistry, Metallurgy
07
J
C07J 41/00 (2006.01) C07J 17/00 (2006.01) A61K 31/705 (1990.01)
Patent
CA 2138839
The present invention is directed to sialic acid derivatives represented by the general formula (I): Image wherein R1 is a steroidal compound residue; R2 is H or alkyl; R3 is alkyl; Image wherein each of R6 and R7 is H, alkyl or the like and I is an integer of 0 to 6; or the like; X is O or S; R4 is H or acyl; and R5 is R14O- (R14 is H or acyl) or R15NH-(R15 is acyl or the like); their salts, hydrates or solvates. Sialic acid derivatives of the present invention are expected to be effective medicines for the prevention and therapy of senile dementia including Alzheimer's disease and the like, because they increase ChAT activity in cholinergic neurons.
Ando Naoko
Chaki Haruyuki
Morinaka Yasuhiro
Saito Ken-Ichi
Yoshida Rie
Ando Naoko
Chaki Haruyuki
Kirby Eades Gale Baker
Mitsubishi Chemical Corporation
Morinaka Yasuhiro
LandOfFree
Sialic acid derivatives does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Sialic acid derivatives, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Sialic acid derivatives will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1380377