Sialic acid glycosides, antigens, immunoadsorbents, and...

Details Sialic acid glycosides, antigens, immunoadsorbents, and... Sialic acid glycosides, antigens, immunoadsorbents, and...

C - Chemistry, Metallurgy

07

H

260/228, 167/37,

C07H 15/04 (2006.01) A61K 39/385 (2006.01) A61K 47/48 (2006.01) C07H 13/04 (2006.01) C07H 15/18 (2006.01) C12Q 1/48 (2006.01) G01N 33/531 (2006.01) G01N 33/574 (2006.01) G01N 33/66 (2006.01)

Patent

CA 1340887

The stereochemistry of sialylation of an acceptor saccharide to obtain an .alpha. (2-3) or .alpha. (2-6) linkage is controlled to favor the .alpha. anomer by use of an aromatic ester of the sialyl reagent. The resulting intermediate .alpha. (2-3) and .alpha. (2-6) sialylated intermediate disaccharide blocks are useful in the synthesis of antigenic substances which can be used to raise antibodies useful in diagnosis and therapy, and can themselves be used as reagents in various applications. The preparation of the tetrasaccharide antigens corresponding to the 19-9 and sialyl-X antigens characteristic of malignant tissue illustrates the application of this method.

584506

Affiliated with

Also associated with

Rating

Sialic acid glycosides, antigens, immunoadsorbents, and... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Sialic acid glycosides, antigens, immunoadsorbents, and..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Sialic acid glycosides, antigens, immunoadsorbents, and... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1231839