C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/12 (2006.01) A61K 31/7088 (2006.01) C07H 21/00 (2006.01) C07K 14/18 (2006.01) C12N 5/10 (2006.01) C12N 15/66 (2006.01) C12Q 1/68 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2417707
The present invention relates to nucleic acids encoding SID® polypeptides which are encoded by a said nucleic acids. The invention also concerns vectors comprising a nucleic acid encoding a SID® polypeptide as well as host cells transformed with such vectors. The invention is also directed to two- hybrid methods which make use of the nucleic acids encoding a SID® polypeptide selected from a pathogenic strain of the hepatitis C virus as well as to methods for selecting molecules which inhibit the binding between a SID® polypeptide and a polypeptide which specifically binds thereto.
Cette invention a trait à des acides nucléiques codant des polypeptides SID® ainsi qu'à ces polypeptides. L'invention porte également sur des vecteurs renfermant un acide nucléique codant un polypeptide SID® ainsi que sur des cellules hôtes transformées par ces vecteurs. Elle concerne, de plus, deux techniques hybrides utilisant les acides nucléiques codant un polypeptide SID® issu d'une souche pathogène de virus de l'hépatite C ainsi que des techniques permettant de sélectionner des molécules inhibant la liaison entre un polypeptide SID® et un polypeptide se liant, de manière spécifique, à celui-ci.
Legrain Pierre
Whiteside Simon
Wojcik Jerome
Fetherstonhaugh & Co.
Hybrigenics
LandOfFree
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