Sigma receptor inhibitors

Details Sigma receptor inhibitors Sigma receptor inhibitors

C - Chemistry, Metallurgy

07

D

C07D 231/54 (2006.01) A61K 31/4439 (2006.01) A61K 31/454 (2006.01) A61K 31/4725 (2006.01) A61K 31/496 (2006.01) A61K 31/5377 (2006.01) A61K 31/541 (2006.01) A61K 31/55 (2006.01) A61P 25/22 (2006.01) A61P 29/00 (2006.01) A61P 37/06 (2006.01) C07D 401/06 (2006.01) C07D 403/06 (2006.01) C07D 417/06 (2006.01) C07D 491/10 (2006.01)

Patent

CA 2577089

The invention relates to compounds having pharmacological activity towards the sigma receptor, and more particularly to pyrazole derivatives of formula (I) and to processes of preparation of such compounds, to pharmaceutical compositions comprising them, and to their use therapy and prophylaxis, in particular for the treatment of psychosis or pain.

La présente invention a pour objet des composés possédant une activité pharmacologique vis-à-vis du récepteur sigma, et plus particulièrement des dérivés de pyrazole de formule I, ainsi que des procédés de synthèse desdits composés. La présente invention a également pour objet des préparations pharmaceutiques comprenant lesdits composés, ainsi que leur utilisation dans un cadre thérapeutique ou prophylactique, plus particulièrement dans le traitement de la psychose ou de la douleur.

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