Sigma receptor ligands and the use thereof

C - Chemistry – Metallurgy – 07 – C

Patent

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Details

C07C 211/26 (2006.01) A61K 31/135 (2006.01) A61K 31/40 (2006.01) A61K 31/445 (2006.01) A61K 31/495 (2006.01) C07C 211/27 (2006.01) C07C 211/28 (2006.01) C07C 211/29 (2006.01) C07C 211/42 (2006.01) C07C 215/28 (2006.01) C07C 215/30 (2006.01) C07C 219/10 (2006.01) C07C 219/12 (2006.01) C07C 225/16 (2006.01) C07C 309/46 (2006.01) C07D 211/08 (2006.01) C07D 211/14 (2006.01) C07D 211/18 (2006.01) C07D 211/22 (2006.01) C07D 211/32 (2006.01) C07D 211/52 (2006.01) C07D 211/70 (2006.01) C07D 295/03 (2006.01) C07D 29

Patent

CA 2166100

The invention relates to methods for the treatment of central nervous system disorders, neurological disorders, gastrointestinal disorders, drug abuse, angina, migraine, hypertension and depression by administering a pharmaceutical composition comprising an effective amount of certain sigma receptor ligands to a patient in need of such treatment. The invention further relates to novel sigma receptor ligands having high binding to the sigma receptor and pharmaceutical compositions thereof.

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