Signal pathway alterations and drug target elevations in...

Details Signal pathway alterations and drug target elevations in... Signal pathway alterations and drug target elevations in...

G - Physics

01

N

G01N 33/574 (2006.01)

Patent

CA 2733010

The present invention relates to the identification and diagnostic use of biomarkers in primary colorectal cancer tu-mors whose activation level are predictive of the likelihood of the onset of metastatic disease. These biomarkers may be used to determine the suitability of a patient for aggressive and/or targeted treatments. Kits and compositions of the invention are also pro-vided.

La présente invention concerne lidentification et lutilisation diagnostique de biomarqueurs dans des tumeurs de cancer colorectal primaire dont le niveau dactivation est prédictif de la probabilité de lapparition dune maladie métastasique. Ces biomarqueurs peuvent être utilisés pour déterminer la compatibilité dun patient avec des traitements agressifs et/ou ciblés. La présente invention concerne en outre des trousses et des compositions.

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