C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 14/315 (2006.01) A61K 31/7088 (2006.01) A61K 38/10 (2006.01) A61K 38/16 (2006.01) A61K 39/395 (2006.01) A61K 48/00 (2006.01) A61P 31/04 (2006.01) C07K 7/08 (2006.01) C12P 21/02 (2006.01)
Patent
CA 2630088
The present invention provides isolated polypeptides capable of inhibiting S. mutans genetic competence and S. mutans biofilm formation. The present invention further provides peptide analogs of S. mutans competence stimulating peptides, compositions thereof, and uses thereof for inhibiting biofilm formation in streptococci and for the treatment and prevention of conditions caused by dental plaque associated streptococci.
L'invention concerne des polypeptides isolés capables d'inhiber la compétence génétique de S. mutans et la formation de biofilm de S. mutans. On décrit aussi des analogues peptidiques de peptides stimulant la compétence de S. mutans, des compositions correspondantes, et des utilisations correspondantes qui permettent d'inhiber la formation de biofilm dans les streptocoques et de traiter et de prévenir les affections engendrées par les streptocoques associés à la plaque dentaire.
Cvitkovitch Dennis G.
Huang Yi-Chen Cathy
Levesque Celine
Madhyastha Srinivasa
Kane Biotech Inc.
Ridout & Maybee Llp
The Governing Council Of The University Of Toronto
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