C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 14/815 (2006.01) A61P 7/02 (2006.01) C07K 14/21 (2006.01) C07K 14/24 (2006.01) C07K 14/245 (2006.01) C12N 1/21 (2006.01) C12N 9/02 (2006.01) C12N 15/62 (2006.01) C12N 15/70 (2006.01)
Patent
CA 2385287
The present invention relates to a hirudin precursor comprising a signal sequence and the sequence of Leu-hirudin, to its preparation and use, and to a process for finding signal sequences for secretory expression of any desired proteins in E. coli and process for the secretory expression of any desired proteins in E. coli.
La présente invention concerne un précurseur d'hirudine comprenant une séquence de signaux et la séquence de leu-hirudine, sa fabrication et son utilisation, ainsi qu'un procédé destiné à déterminer des séquences de signaux pour l'expression sécrétoire de protéines quelconques dans E. coli, et un procédé pour l'expression sécrétoire de protéine quelconques dans E. coli.
Bender Rudolf
Habermann Paul
Aventis Pharma Deutschland Gmbh
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Sanofi-Aventis Deutschland Gmbh
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