Siliceous support media for immobilization of enzymes

Details Siliceous support media for immobilization of enzymes Siliceous support media for immobilization of enzymes

C - Chemistry, Metallurgy

12

N

C12N 11/00 (2006.01) C12N 9/02 (2006.01) C12N 9/24 (2006.01) C12N 11/14 (2006.01) C12P 13/00 (2006.01) C12P 13/22 (2006.01)

Patent

CA 2277371

A simple, efficient method for immobilization of enzymes on siliceous supports is reported. The support and the enzyme are linked using a polyfunctional cross-linking agent such as glutaraldehyde. Owing to properties peculiar to siliceous supports, the resulting immobilized enzyme is much more stable than enzymes immobilized on other supports. Consequently, much less enzyme is required. The immobilized enzymes generated via this process are ideally suited for continuous enzymatic production of commodity chemicals and pharmaceuticals such as L-DOPA, and for other enzyme-mediated industrial processes.

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