C - Chemistry – Metallurgy – 07 – F
Patent
C - Chemistry, Metallurgy
07
F
C07F 7/08 (2006.01) A61K 31/695 (2006.01) A61P 25/24 (2006.01)
Patent
CA 2464997
A compound of formula (I): wherein R1 and R2 are, independently, hydrogen or alkyl or together, with the nitrogen atom, form a heterocyclyl; R3 and R4 are, independently, hydrogen, hydroxyl, alkyl, alkoxy, alkanoyloxy, cyano, nitro, alkylmercapto, amino, alkylamino, dialkylamino, alkanamido, halogen or trifluoromethyl; R5 is hydrogen or alkyl; and n is 0, 1, 2, 3 or 4; or a pharmaceutically acceptable salt thereof or a prodrug form that is hydrolysable to a compound as defined above.
L'invention concerne un composé représenté par la formule (I) dans laquelle R?1¿ et R?2¿ représentent indépendamment hydrogène ou alkyle ou forment, avec l'atome d'azote, un hétérocyclyle, R?3¿ et R?4¿ représentent indépendamment hydrogène, hydroxyle, alkyle, alcoxy, alcanoyloxy, cyano, nitro, alkylmercapto, amino, alkylamino, dialkylamino, alkanamido, halogène ou trifluorométhyle, R?5¿ représente hydrogène ou alkyle et n vaut 0, 1, 2, 3 ou 4. L'invention concerne également un sel pharmaceutiquement acceptable de ce composé ou une forme de promédicament pouvant être hydrolysée en un composé tel que défini ci-dessus.
Daiss Jurgen
Tacke Reinhold
Amedis Pharmaceuticals Limited
Cassan Maclean
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