Silicon derivatives for pet imaging

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 1/13 (2006.01) A61K 31/695 (2006.01) A61K 51/04 (2006.01) A61K 51/08 (2006.01) C07B 59/00 (2006.01) C07F 7/02 (2006.01)

Patent

CA 2664700

The present invention relates to novel compounds suitable for or already radiolabeled with 18F, methods of making such compounds and use of such compounds for diagnostic imaging. Such labeled vompounds are characerized by Formula II, wherein the moieties F, R1, R2, B1,2, Y1.2,, Z1.2 and E have the meaning as defined in the specification and claims.

La présente invention concerne de nouveaux composés appropriés ou déjà marqués radioactivement au 18F, des procédés de fabrication de tels composés et l'utilisation de tels composés à des fins d'imagerie diagnostique. De tels composés marqués sont caractérisés par la formule II, les groupements F, R1, R2, B1.2, Y1.2, Z1.2 et E ayant une signification telle que définie dans la spécification et les revendications.

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