Silicone elastomer-containing pharmaceutical preparation

A - Human Necessities – 61 – K

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A61K 9/58 (2006.01) A61K 9/00 (2006.01) A61K 9/20 (2006.01)

Patent

CA 1049408

ABSTRACT OF THE DISCLOSURE A pharmaceutical preparation includes a pharmacological- ly active substance such as mestranol, ethinyloestradiol or ethisterone, and an organo-polysiloxane two-component moulding composition of the low-temperature vulcanizing-type containing a silicone copolymer, e.g., a mixture of an organo-polysiloxane having a viscosity of 500 - 200,000 centi-Stokes at 25°C and having the general formula Image in which R represents an alkyl or phenyl residue, and n is a whole number of from 200 to 1600, an organo-polysiloxane copolymer consisting of (a) R'3SiO0.5-units, (b) R'2ViSiO0.5-units and (c) SiO2-units, in which R' represents a monovalent, organic residue containing no unsaturated groups, and an organo-hydrogen- polysiloxane of the general formula Image in which R' ' represents a monovalent residue containing no unsaturated groups, a:b is 0.5 - 10 and a+b is 1 to 2.5. By adding a platinum catalyst to the mixture, vulcanization is effected.

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