C - Chemistry – Metallurgy – 07 – F
Patent
C - Chemistry, Metallurgy
07
F
260/446.5
C07F 7/10 (2006.01)
Patent
CA 1131241
10,875-C-1 ANALYTICAL OR CLINICAL ISOCYANATES DERIVATIVES ABSTRACT OF THE DISCLOSURE Novel isocyanates such as, for example, blocked L-tyrosine methyl ester isocyanate, are reacted with com- pounds of biological, clinical interest or the like such as, for example, digoxin, to form derivatives respective to tagging, as by radiolabeling. The tagged derivatives may then be employed to determine the presence of a compound of interest in nanomolar or even picomolar amounts by using clinical analysis techniques such as radio- immunoassay. RELATED APPLICATION Hedaya and Theodoropulos, Canadian application Serial No. 278,460, for: A Method Of Preparing Halosilyl Carbamates And Isocyanates Derived Therefrom, filed on May 16, 1977. SPECIFICATION
360360
Eisenhardt William A.
Hedaya Eddie
Theodoropulos Spyros
Baker Instruments Corporation
Osler Hoskin & Harcourt Llp
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