Silver-containing foam structure

A - Human Necessities – 61 – L

Patent

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Details

A61L 15/18 (2006.01) A61L 15/24 (2006.01) A61L 15/42 (2006.01)

Patent

CA 2678034

The present invention relates to a method of producing a hydrophilic polyurethane foam structure containing a silver salt, chosen from the group of silver sulphate, silver citrate, silver acetate, silver carbonate, silver lactate and silver phosphate, or a mixture of these salts. The method comprises the steps of (a) providing a water phase containing a surfactant, and at least one silver salt, wherein the at least one silver salt is dispersed in the water phase; (b) providing a isocyanate-terminated polyether having functionality of more than (2); (c) mixing said water phase and said isocyanate-terminated polyether, immediately transferring the resulting mixture to a mould whereby a foam structure is obtained; and (d) drying said foam structure until it has a moisture content of at most 10 % (wt). The invention also provides a hydrophilic polyurethane foam structure produced by the method and a wound dressing containing the foam structure.

La présente invention concerne un procédé destiné à la production d'une structure en mousse de polyuréthane hydrophile contenant un sel d'argent choisi dans le groupe du sulfate d'argent, du citrate d'argent, de l'acétate d'argent, du carbonate d'argent, du lactate d'argent et du phosphate d'argent, ou un mélange de ces sels. Le procédé consiste à (a) fournir une phase aqueuse contenant un tensio-actif et au moins un sel d'argent dispersé dans la phase aqueuse, (b) fournir un polyéther à terminaison isocyanate à fonctionnalité supérieure à (2), (c) mélanger la phase aqueuse et le polyéther à terminaison isocyanate et transférer immédiatement le mélange résultant dans un moule, ce qui permet d'obtenir une structure en mousse, et (d) sécher la structure en mousse jusqu'à ce que la teneur en humidité soit de 10% en poids au maximum. L'invention a aussi pour objet une structure en mousse de polyuréthane hydrophile produite au moyen du procédé et un pansement comprenant la structure en mousse.

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