Silver nanoparticles with specific surface area and a method...

A - Human Necessities – 01 – N

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A01N 59/16 (2006.01) A01N 25/08 (2006.01) A01N 25/34 (2006.01) A01N 63/02 (2006.01) A61K 9/51 (2006.01) C01G 5/00 (2006.01)

Patent

CA 2710827

Silver nanoparticles associated with 20 to 80% by weight of a biocomponent of the genus Lactobacillus, said silver nanoparticles having a ratio of the average particle size to the specific surface area (BET) of from 0.015 to 0.15 nm/m2/g; a method for producing silver nanoparticles, comprising the step of incubating bacteria of the genus Lactobacillus with an aqueous solution comprising at least 4 mM of a silver salt in the presence of ammonia and an alkali metal hydroxide until a biomass of bacteria containing Ag 0 silver nanoparticles is formed; and optionally a further step of extracting said Ag 0 silver nanoparticles from said biomass by means of concentrated alkali metal hydroxide or concentrated inorganic acid or enzymes; an anti-microbial composition comprising an effective amount of said silver nanoparticles; use of said silver nanoparticles for the manufacturing of an article or a composition with anti-microbial activity; a method for manufacturing an article or a composition with anti-microbial activity, comprising dispersing or impregnating said silver nanoparticles into said article or composition; and an article with anti-microbial property having said silver nanoparticles dispersed therein.

L'invention porte sur des nanoparticules d'argent associées à 20 à 80 % en poids d'un biocomposant du genre Lactobacillus, lesdites nanoparticules d'argent ayant un rapport de la taille de particule moyenne à la surface spécifique (BET) de 0,015 à 0,15 nm/m?/g; sur un procédé pour produire des nanoparticules d'argent, comprenant l'étape d'incubation de bactéries du genre Lactobacillus avec une solution aqueuse comprenant au moins 4 mM d'un sel d'argent en présence d'ammoniac et d'un hydroxyde de métal alcalin jusqu'à ce qu'une biomasse de bactéries contenant des nanoparticules d'argent Ag0 soit formée; et, éventuellement, une autre étape d'extraction desdites nanoparticules d'argent Ag0 à partir de la biomasse à l'aide d'un hydroxyde de métal alcalin ou d'un acide minéral concentré ou d'enzymes; sur une composition antimicrobienne comprenant une quantité efficace desdites nanoparticules d'argent; sur l'utilisation desdites nanoparticules d'argent pour la fabrication d'un article ou d'une composition ayant une activité antimicrobienne; sur un procédé pour la fabrication d'un article ou d'une composition ayant une activité antimicrobienne, comprenant la dispersion ou l'imprégnation desdites nanoparticules d'argent dans ledit article ou ladite composition; et sur un article ayant une propriété antimicrobienne, ayant lesdites nanoparticules d'argent dispersées à l'intérieur de celui-ci.

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