Simian adenovirus 41 and uses thereof

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 7/00 (2006.01) A61K 39/145 (2006.01) A61K 48/00 (2006.01) C07K 14/075 (2006.01) C12N 15/861 (2006.01)

Patent

CA 2762203

Novel simian adenovirus 41 and two isolates thereof are described. Various uses of these isolates, including construction of a recombinant vector which comprises simian adenovirus 41 sequences and a heterologous gene under the control of regulatory sequences are provided. A cell line which expresses simian adenovirus 41 gene(s) is also disclosed. Methods of using the vectors and cell lines are provided.

L'invention concerne un nouvel adénovirus simien 41 et deux de ses isolats. L'invention concerne également diverses utilisations de ces isolats, y compris la construction d'un vecteur recombinant qui comprend des séquences d'adénovirus simien 41 et un gène hétérologue sous le contrôle de séquences de régulation. Une lignée cellulaire qui exprime un ou plusieurs gènes de l'adénovirus simien 41 est également décrite. Des procédés d'utilisation des vecteurs et des lignées cellulaires sont également décrits.

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