Simian orl1 gene and method of assessing compound

C - Chemistry – Metallurgy – 12 – N

Patent

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C12N 15/12 (2006.01) C07K 14/705 (2006.01) C12N 1/15 (2006.01) C12N 1/19 (2006.01) C12N 1/21 (2006.01) C12N 5/10 (2006.01) C12Q 1/02 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2544821

A nucleic acid having a base sequence of SEQ ID NO. 1; a protein having an amino acid sequence of SEQ ID NO. 2; a recombinant vector comprising a gene constituted of the above nucleic acid; and a transformant cell comprising the recombinant vector. By the use of these, it is feasible to provide ORL1 gene of non-human primates, etc. and to perform assessment, screening, etc. of compounds acting on the ORL1.

Un acide nucléique possède une séquence de base de SEQ ID NO. 1, une protéine possédant une séquence d'acides aminés de SEQ ID NO. 2, un vecteur recombinant comprenant un gène constitué de l'acide nucléique susmentionné, et une cellule transformante comprenant le vecteur recombinant. L'utilisation de ces produits permet de produire un gène ORL1 de primates non humains, etc., et de faire une estimation, un criblage, etc., de composés agissant sur ORL1.

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