Simian subfamily b adenovirus sadv-28, -27, -29, -32, -33...

Details Simian subfamily b adenovirus sadv-28, -27, -29, -32, -33... Simian subfamily b adenovirus sadv-28, -27, -29, -32, -33...

C - Chemistry, Metallurgy

12

N

C12N 15/861 (2006.01) C12N 7/00 (2006.01)

Patent

CA 2706257

A recombinant vector comprises simian adenovirus 28, simian adenovirus 27, simian adenovirus 32, simian adenovirus 33, and/or simian adenovirus 35 sequences and a heterologous gene under the control of regulatory sequences. A cell line which expresses one or more simian adenovirus - 28, -27, - 32, -33, or -35 genes is also disclosed. Methods of using the vectors and cell lines are provided.

L'invention concerne un vecteur recombinant qui comprend des séquences adénovirales simiennes 28, 27, 32, 33, et/ou 35 et un gène hétérologue sous le contrôle de séquences régulatrices. Elle concerne également une lignée cellulaire exprimant un ou plusieurs gènes adénoviraux simiens - 28, -27, - 32, -33, ou -35. Elle concerne enfin, des procédés d'utilisation de ces vecteurs et de ces lignées cellulaires.

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