Simplified sarcodictyn derivatives as anti-tumor agents

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 233/54 (2006.01) A61K 31/415 (2006.01) A61K 31/42 (2006.01) A61K 31/425 (2006.01) A61K 31/44 (2006.01) A61K 31/695 (2006.01) A61P 35/00 (2006.01) C07C 69/013 (2006.01) C07C 69/16 (2006.01) C07C 69/618 (2006.01) C07D 213/30 (2006.01) C07D 233/90 (2006.01) C07D 263/32 (2006.01) C07D 263/34 (2006.01) C07D 277/24 (2006.01) C07D 277/30 (2006.01)

Patent

CA 2460244

There are provided sarcodictyin derivatives or pharmaceutically acceptable salts thereof, which are characterized by a simplified chemical structure and have anti-tumor activity. A process for their preparation, the pharmaceutical compositions containing them, and their use in the prevention, control and treatment of cancer are also provided.

L'invention concerne des dérivés de sarcodictyne ou des sels de qualité pharmaceutique de ces dérivés, se caractérisant par une structure chimique simplifiée et une activité antitumorale. L'invention concerne également un procédé destiné à la préparation de ces dérivés, des compositions pharmaceutiques renfermant ces dérivés et leur utilisation dans la prévention, le dépistage et le traitement du cancer.

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