Simulating patient-specific outcomes

G - Physics – 06 – F

Patent

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G06F 19/00 (2011.01)

Patent

CA 2540280

The invention encompasses systems, methods, and apparatus for predicting and monitoring an individual~s response to a therapeutic regimen. The invention includes multiple virtual patients, an associating subsystem operable to associate the subject with one or more of the virtual patients, and a simulation engine operable to apply one or more experimental protocols to the one or more virtual patients identified with the subject to generate a set of outputs. The set of outputs can represent therapeutic efficacy, identify biomarkers for monitoring therapeutic efficacy, or merely report the status of the biological system as it represents a particular individual.

L'invention concerne des systèmes, des méthodes ainsi qu'un appareil permettant de prédire et de contrôler la réponse d'un individu à un schéma thérapeutique. L'invention comprend de multiples patients virtuels, un sous-système d'association permettant d'associer le sujet à un ou à plusieurs des patients virtuels, et un moteur de simulation permettant d'appliquer un ou plusieurs protocoles expérimentaux à un ou à plusieurs patients virtuels identifiés au moyen du sujet pour générer un ensemble de sorties. L'ensemble de sorites peut représenter une efficacité thérapeutique, identifier des biomarqueurs de contrôle de l'efficacité thérapeutique ou simplement rapporter l'état du système biologique tel qu'il représente un individu particulier.

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