Simultaneous heterogeneous specific binding assay of...

Details Simultaneous heterogeneous specific binding assay of... Simultaneous heterogeneous specific binding assay of...

G - Physics

01

N

150/11, 167/37

G01N 33/543 (2006.01)

Patent

CA 1128856

ABSTRACT OF THE DISCLOSURE A heterogeneous specific binding assay method and test means for the simultaneous determination of each of a plur- ality of different ligands (e.g., antibodies, antigens or haptens) in a single liquid test sample. The assay may follow any conventional technique of a heterogeneous type, i.e., which includes a separation of a bound-species from a free-species form of the labeled reagent. The combined assay is accomplished by using solid-phase binding agents for the respective ligands to be determined which are differentially separable from each other, thereby permitting the use of a single label rather than a different label for each ligand to be determined. The assay is particularly suited to the simultaneous determination of different antibodies, particu- larly antibodies to different viral antigens, in a single serum sample.

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