Single amino acid based compounds for counteracting effects...

Details Single amino acid based compounds for counteracting effects... Single amino acid based compounds for counteracting effects...

A - Human Necessities

61

K

A61K 31/198 (2006.01) A61K 47/06 (2006.01) A61K 47/48 (2006.01) A61P 39/06 (2006.01) C07C 229/24 (2006.01)

Patent

CA 2448062

Single amino acid compounds and methods for upregulating expression of a gene encoding an antioxidative enzyme, such as superoxide dismutase or catalase, to counteract harmful oxidative effects of reactive oxygen species and other free radicals are described. The single amino acid compounds may be used in compositions and methods to treat or prevent diseases and conditions characterized by undesirable elevation of reactive oxygen species and other free radicals.

L'invention porte sur des composés contenant un seul acide aminé et des procédés de régulation positive de l'expression d'un gène codant une enzyme anti-oxydante, telle que la superoxyde dismutase ou catalase, afin de parer aux effets oxydants nocifs des espèces d'oxygène réactif et d'autres radicaux libres. Les composés à un seul acide aminé peuvent être utilisés dans des compositions et des procédés destinés à traiter ou prévenir des maladies et des pathologies caractérisées par l'augmentation indésirable d'espèces d'oxygène réactif et d'autres radicaux libres.

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