Single-chain polypeptides comprising troponin i n-terminal...

C - Chemistry – Metallurgy – 12 – N

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C12N 15/12 (2006.01) C07K 14/47 (2006.01) C12N 1/21 (2006.01) C12N 15/62 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2381439

This invention relates to single-chain polypeptides and their genetic sequences comprising a human cardiac troponin I N-terminal fragment and troponin C. The N-terminal fragment may or may not have the intact N-terminus. The single-chain polypeptide may be expressed recombinantly, and a linker or spacer polypeptide or peptide may be interposed between the troponin sequences. The single-chain polypeptides have utility as controls or calibrators for troponin assays, for the purification of troponin subunits and as an antigen for the preparation of antibodies.

L'invention concerne des polypeptides à chaîne unique et leurs séquences génétiques comprenant un fragment N-terminal de troponine I cardiaque humaine et de la troponine C. Le fragment N-terminal peut présenter ou non la N-terminaison intacte. Le polypeptide à chaîne unique peut être exprimé par recombinaison, et un peptide ou polypeptide espaceur ou de liaison peut être interposé entre les séquences de troponine. Les polypeptides à chaîne unique sont utiles comme agents de régulation ou d'étalonnage pour les dosages de troponine, pour la purification de sous-unités de troponine, ainsi que comme antigène pour la préparation d'anticorps.

LandOfFree

Say what you really think

Search LandOfFree.com for Canadian inventors and patents. Rate them and share your experience with other people.

Rating

Single-chain polypeptides comprising troponin i n-terminal... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Single-chain polypeptides comprising troponin i n-terminal..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Single-chain polypeptides comprising troponin i n-terminal... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFCA-PAI-O-2048428

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.