Single device for ion mobility and ion trap mass spectrometry

Details Single device for ion mobility and ion trap mass spectrometry Single device for ion mobility and ion trap mass spectrometry

G - Physics

01

N

G01N 27/00 (2006.01) H01J 49/40 (2006.01)

Patent

CA 2529597

A single set of electrodes, wherein different electrical potentials are applied to the single set of electrodes at different times in order to perform both ion mobility-based spectrometry and mass spectrometry (MS) on a sample of ions, wherein the ions are processed by performing ion mobility-based spectrometry and mass spectrometry in any sequence, any number of times, and as isolated or superposed procedures in order to trap, separate, fragment, and/or analyze charged particles and charged particles derived from atoms, molecules, particles, sub-atomic particles and ions. The present invention is a single device (10) that is able to perform both mass spectrometry and FAIMS shown as a circular rod electrode (12) disposed coaxially with an outer cylindrical electrode (14). In order to perform FAIMS, the circular rod electrode (12) is typically held at a constant potential or at ground, and an asymmetric FAIMS waveform is applied to the outer cylindrical electrode (14).

La présente invention a trait à un ensemble unique d'électrodes, dans lequel différents potentiels électriques sont appliqués à l'ensemble unique d'électrodes à des instants différents en vue de réaliser à la fois la spectrométrie à mobilité ionique et la spectrométrie de masse sur des échantillons d'ions, les ions étant traités par la réalisation de la spectrométrie à base de mobilité ionique et de la spectrométrie de masse dans une séquence quelconque, pour un nombre de fois quelconque, et sous la forme de procédés isolés ou superposés pour effectuer le piégeage, la séparation, la fragmentation, et/ou l'analyse de particules chargées et de particules chargées dérivées d'atomes, de molécules, de particules, de particules subatomiques et d'ions.

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