Single nucleotide polymorphisms in gh-1

Details Single nucleotide polymorphisms in gh-1 Single nucleotide polymorphisms in gh-1

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01) C07K 14/61 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2466346

The invention provides nucleic acid segments of the GH-1 gene including polymorphic sites. Allele specific primers and probes hybridizing to regions flanking these sites are also provided. The invention also provides methods for diagnosing GH-1 dysfunction.

L'invention concerne des segments d'acide nucléique du gène de l'hormone de croissance GH-1 comprenant des sites polymorphes. Des amorces spécifiques d'allèles et des sondes s'hybride avec des zones flanquant ces sites sont également décrites. L'invention concerne en outre des procédés de diagnostic d'une dysfonction de l'hormone de croissance GH-1.

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