A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
167/310
A61K 47/24 (2006.01) A61K 8/70 (2006.01) A61K 9/00 (2006.01) A61K 9/06 (2006.01) A61K 47/22 (2006.01)
Patent
CA 1323578
1. "SINGLE-PHASE COMPOSITION CONTAINING A PERFLUORINATED OIL AND ONE OR MORE SURFACTANT(S), USEFUL AS AN EXCIPIENT FOR COSMETIC AND DERMATOLOGIC FORMULATIONS, AS WELL AS FOR BIOMEDICAL APPLICATIONS" Abstract A single-phase, either isotropic or anisotropic formulation is disclosed, which contains perfluorinated oil and one or more surfactant(s), Is useful as an excipient for cosmetic and dermatologic formulations and is characterized in that at least one surfactant is selected from those having the following general formula: Image wherein: RF is an F-(CF2-CH2)i- X is a group selected from: Image ; -(CH2-CH2-OK)-; Image ; -(CH2-CH2-S)K-; -(CH2-O)K-; and -(CH2-S)K-; wherein R is a (C1-C4)-alkyl; Y is a group selected from: 2. NH2(RII)2 and N(RII)4; wherein RII is a hydrogen atom, or a group selected from -CH2-CH2-OH and (C1-C4)-alkyl; i is an integer comprised within the range ot from 3 to 8; j is zero or 1; K is 2.L; l is an integer comprised within the range of from 1 to 10; m is 1 or 2. Such composition is spontaneously formed when the components are simply placed into contact with one another. In particular, in case of the isotropic form, the composition is a fluid, clear and stable composition, with particle size smaller than 400 A, containing: (a) from 1 to 50% by weight of the perfluorinated oil; (b) from 1 to 50% by weight of water; (c) from 8 to 60% by weight of at least one surfactant selected from the above defined surfactants; (d) from 6 to 38X by weight of a co-surfactant, selected from (C3-C7)-aliphatic alcohols. In case of the anisotropic form, the composition has a high viscosity, and contains: (a) from 1 to 50% by weight of the perfluorinated oil; (b) from 1 to 80% by weight of water; (c) from 1 to 40% by weight of at least one surfactant selected from the above defined surfactants; (d) from 0 to 19% by weight of a co-surfactant, selected from (C3-C7)-aliphatic alcohols. Furthermore, in case of the isotroplc composition this latter finds also use in the biomedical sector.
569542
Borgarello Enrico
Carlini Filippo M.
Neri Carlo
Platone Edoardo
Borgarello Enrico
Carlini Filippo M.
Enichem Synthesis S.p.a.
Eniricerche S.p.a.
Neri Carlo
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