Single-time vaccines

Details Single-time vaccines Single-time vaccines

A - Human Necessities

61

K

A61K 39/095 (2006.01) A61K 9/127 (2006.01) A61P 37/04 (2006.01)

Patent

CA 2744048

The present invention relates to the field of vaccines, in particular to a vaccine formulation containing the proteoliposome derived from the external membrane of Neisseria meningitidis serogroup B(AFPL1) or the cochleate derivative (AFCoI) thereof, alone or jointly with one or more microbial or tumoural antigens, and furthermore the use of said vaccine formulation in the prevention and treatment of infections or tumoural diseases through the simultaneous administration thereof by both the mucosal and parenteral routes of administration.

La présente invention concerne le domaine des vaccins et, plus particulièrement, une préparation vaccinale qui contient le protéoliposome dérivé de la membrane externe de Neisseria meningitidis sérogroupe B (AFPLl) ou son dérivé cochléaire (AFCoI), seuls ou en combinaison avec un ou plusieurs antigènes microbiens ou tumoraux, ainsi que l'utilisation de ladite préparation vaccinale pour la prévention et le traitement d'infections ou de maladies tumorales par administration simultanée par deux voies d'administration, à savoir mucosale et parentérale.

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