C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 221/28 (2006.01) A61K 31/485 (2006.01) A61P 25/28 (2006.01) C07D 489/00 (2006.01)
Patent
CA 2507067
The invention relates to sinomenine and compounds thereof and also to compounds of formula (I), wherein R1 represents an alkyl group; R2 represents a hydrogen atom or an alkylcarbonyl group, an haloalkylcarbonyl group or an arylcarbonyl; Y represents a group (II), (III) or (IV); R3 ,R4, R~4, R5, R~5 and R6 are as defined in the description; and X represents a halogen atom. Medicaments.
L'invention concerne la sinoménine et des composés de cette substance, ainsi que des composés de formule (I), dans laquelle R¿1? représente un groupe alkyle, R¿2? représente un atome d'hydrogène ou un groupe alkylcarbonyle, haloalkylcarbonyle ou arylcarbonyle, Y représente un groupe (II), (III) ou (IV), R¿3?, R¿4?, R'¿4?, R¿5?, R'¿5? et R¿6? ont les significations indiquées dans la description et X représente un atome d'hydrogène. L'invention concerne également des médicaments.
Caignard Daniel-Henri
Lestage Pierre
Qin Guo-Wei
Renard Pierre
Tang Xi-Can
Les Laboratoires Servier
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
Shanghai Institute Of Materia Medica Chinese Academy Of Sciences
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