Sirna for control of gene expression

Details Sirna for control of gene expression Sirna for control of gene expression

C - Chemistry, Metallurgy

12

N

C12N 15/11 (2006.01) C12N 15/113 (2010.01) A61K 31/7105 (2006.01) C12N 15/85 (2006.01)

Patent

CA 2487328

The present invention relates generally to a method of modifying gene expression and to synthetic genes for modifying endogenous gene expression in a cell, tissue or organ of a transgenic organism, in particular a transgenic animal or plant. More particularly, the present invention utilizes recombinant DNA technology to post-transcriptionally modify or modulate the expression of a target gene in a cell, tissue, organ or whole organism, thereby producing novel phenotypes. Novel synthetic genes and genetic constructs which are capable of repressing delaying or otherwise reducing the expression of an endogenous gene or a target gene in an organism when introduced thereto are also provided.

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