C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/11 (2006.01) A61K 31/713 (2006.01) C12N 5/10 (2006.01) C12N 7/00 (2006.01)
Patent
CA 2457419
The present invention relates to polynucleotide constructs, methods for their preparation, and preparations for their use in methods that lower the amount of RNA and/or protein production in cells based on the intracellular expression of small interfering polyribonucleic acid molecules.
La présente invention concerne des constructions polynucléotidiques, leurs procédés de préparation et les préparations permettant leur utilisation dans des procédés qui réduisent la quantité de production d'ARN et/ou de protéines dans les cellules sur la base de l'expression intracellulaire de petites molécules d'acide polyribonucléique interférant.
Arts Gert-Jan
Langemeijer Ellen Vera
Michiels Godefridus Augustinus Maria
Piest Ivo
Van Es Helmuth Hendrikus Gerardus
Fetherstonhaugh & Co.
Galapagos Genomics N.v.
Galapagos N.v.
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