Sirna mediated gene silencing in transgenic animals

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/11 (2006.01) C12N 5/10 (2006.01) C12N 15/63 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2502664

The present invention relates to a process that enables constitutive and inducible gene knock down in living organisms using a short hairpin RNA expression vector integrated into the genome of the organism.

La présente invention porte sur un procédé qui permet l'inhibition d'un gène constitutif et inductible dans des organismes vivants en utilisant un vecteur d'expression de l'ARN à courte structure en épingle à cheveux intégré au génome de l'organisme.

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