Sirna-mediated gene silencing with viral vectors

C - Chemistry – Metallurgy – 12 – Q

Patent

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Details

C12Q 1/68 (2006.01) A01N 43/04 (2006.01) A01N 63/00 (2006.01) C12N 5/00 (2006.01) C12N 15/00 (2006.01) C12N 15/11 (2006.01) C12N 15/63 (2006.01) C12P 19/34 (2006.01) A61K 38/00 (2006.01) A61K 48/00 (2006.01)

Patent

CA 2494859

The present invention is directed to viral vectors encoding small interfering RNA molecules (siRNA) targeted against a gene of interest, and methods of using these viral vectors.

La présente invention concerne des vecteurs viraux codant des molécules d'ARN à faible interférence (ARNsi) dirigés contre un gène à étudier ainsi que des méthodes d'utilisation desdits vecteurs viraux.

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