C - Chemistry – Metallurgy – 07 – H
Patent
C - Chemistry, Metallurgy
07
H
C07H 21/02 (2006.01) A61K 9/127 (2006.01) A61K 47/44 (2006.01) A61K 48/00 (2006.01) C12N 15/88 (2006.01)
Patent
CA 2587411
The present invention provides nucleic acid-lipid particles comprising siRNA molecules that silence ApoB expression and methods of using such nucleic acid- lipid particles to silence ApoB expression.
La présente invention concerne des particules d'acide nucléique-lipide contenant des molécules ARNsi qui rend silencieuse l'expression de ApoB. L'invention concerne également les procédés utilisant de telles particules d'acide nucléique-lipide pour rendre silencieuse l'expression de ApoB.
Jeffs Lloyd B.
Judge Adam
Lee Amy C. H.
Maclachlan Ian
Palmer Lorne R.
Fetherstonhaugh & Co.
Protiva Biotherapeutics Inc.
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