C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 487/04 (2006.01) A61K 31/4985 (2006.01) A61P 3/10 (2006.01) C07C 227/16 (2006.01) C07C 227/34 (2006.01) C07C 229/34 (2006.01)
Patent
CA 2759077
The present invention relates to novel processes for the preparation of enantiomerically enriched ß -amino acid derivatives such as ß -amino esters useful for the synthesis of enantiomerically enriched biologically active molecules such as sitagliptin. The key step involves the resolution of the racemate with mandelic acid.
La présente invention a pour objet de nouveaux procédés pour la préparation de dérivés d'acide ß-aminé énantiomériquement enrichis tels que les ß-aminoesters utiles pour la synthèse de molécules biologiquement actives énantiomériquement enrichies telles que la sitagliptine. L'étape clé implique la résolution du racémate avec de l'acide mandélique.
Bhosle Priyanka
Gadakar Maheshkumar
Gore Vinayak Govind
Shinde Suresh
Generics [uk] Limited
Osler Hoskin & Harcourt Llp
LandOfFree
Sitagliptin synthesis does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Sitagliptin synthesis, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Sitagliptin synthesis will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1424344