Site-specific coupling of polypeptides

Details Site-specific coupling of polypeptides Site-specific coupling of polypeptides

C - Chemistry, Metallurgy

07

K

C07K 14/485 (2006.01) C07K 17/10 (2006.01)

Patent

CA 2544762

The present invention relates to a method of modifying a polypeptide, which yields a modifed polypeptide, suitable for site-specific coupling, for example, as a targeting ligand, as well as modified human EGF and fragments thereof, suitable for site-specific coupling.

L'invention concerne un procédé permettant de modifier un polypeptide, produisant ainsi un polypeptide modifié approprié au couplage spécifique au site, par exemple comme un ligand de ciblage, ainsi qu'un facteur de croissance épidermique (EGF) humain et des fragments de celui-ci, convenant au couplage spécifique au site.

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