Site specific listeria integration vectors and methods for...

Details Site specific listeria integration vectors and methods for... Site specific listeria integration vectors and methods for...

C - Chemistry, Metallurgy

12

N

C12N 15/74 (2006.01) A61K 39/02 (2006.01) C12N 1/21 (2006.01)

Patent

CA 2484185

Site-specific Listeria integration vectors and methods for their use are provided. The subject vectors include a bacteriophage integrase gene and a bacteriophage attachment site, where in many embodiments the bacteriophage that is the source of these elements is a listeriophage. In certain embodiments, the subject vectors further include a multiple cloning site, where the multiple cloning site may further include a polypeptide coding sequence, e.g., for a heterologous antigen. The subject vectors and methods find use in a variety of different applications, including the study of Listeria species and the preparation of Listeria vaccines.

L'invention concerne des vecteurs d'intégration de la listéria spécifiques d'un site et leurs méthodes d'utilisation. Les vecteurs du sujet comprennent un gène de l'intégrase bactériophage et un site de fixation bactériophage. Dans plusieurs modes de réalisation, le bactériophage source desdits éléments est un listériophage. Dans certains modes de réalisation, les vecteurs comprennent un site de clonages multiples, ledit site comprenant en outre une séquence de codage polypeptidique, par exemple, un antigène hétérologue. Ces vecteurs et ces méthodes sont utilisés dans une variété d'applications différentes, notamment l'étude des espèces de listéria et la préparation des vaccins contre la listéria.

Affiliated with

Also associated with

Rating

Site specific listeria integration vectors and methods for... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Site specific listeria integration vectors and methods for..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Site specific listeria integration vectors and methods for... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1579149