Skin-derived precursor cells and uses thereof

A - Human Necessities – 61 – K

Patent

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A61K 35/36 (2006.01) A61L 27/38 (2006.01) A61L 27/58 (2006.01) A61L 27/60 (2006.01) A61P 17/02 (2006.01) A61P 17/14 (2006.01)

Patent

CA 2689484

The invention features methods of inducing hair follicle formation in a mammal by transplantation of skin-derived precursors (SKPs) and keratinocytes into the skin of the mammal. The invention also features compositions and kits including SKPs and keratinocytes. In other aspects, the invention features methods for producing dermal sheets from SKPs, methods for using such sheets and dermal sheets produced by SKPs.

L'invention concerne des procédés induisant la formation de follicules pileux chez un mammifère par transplantation de précurseurs issus de la peau (SKP) et de kératinocytes dans la peau du mammifère. L'invention concerne également des compositions et des coffrets comprenant des SKP et des kératinocytes. Sous d'autres aspects, l'invention concerne des procédés de production de feuillets dermiques à partir de SKP, des procédés d'utilisation de tels feuillets et des feuillets dermiques produits par les SKP.

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