Skin treatment apparatus for sustained transdermal drug...

A - Human Necessities – 61 – M

Patent

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Details

A61M 37/00 (2006.01)

Patent

CA 2393537

An expandable skin stretching device (100) includes skin engaging opposite ends (56, 57) that contact the skin (30) surface on opposite sides of an area of the skin surface having micropathways (31) therein. When the skin stretching device (100) is expanded the skin (30) between the opposite ends (56, 57) is placed under tension, i.e., stretched. The skin is placed under a tension of about 0.01 to about 10 megapascals, preferably about 0.05 to about 2 megapascals. The skin stretching can be uni-directional or multi-directional. Alternative embodiments of skin stretching devices (101, 102, 103, 104, 105) use suction or normal force to stretch the skin (30). Stretching the skin (30) helps keep the micropathways (31) open for enhanced agent (e.g., drug) delivery through the micropathways (31). The stretching also delays micropathway (31) closure. Image

L'invention concerne un dispositif (100) extensible d'étirement de la peau. Ce dispositif comprend des extrémités (56, 57) opposées de contact cutané qui entrent en contact avec la surface de la peau (30) sur les côtés opposés d'une zone de surface cutanée qui présente des micro-voies (31). Lorsque le dispositif (100) d'étirement de la peau se trouve en extension, la peau (30) située entre les extrémités (56, 57) opposées est mise sous tension, ou étirée. La peau est soumise à une tension allant de 0,01 à 10 mégapascals environ, de préférence de 0,05 à 2 mégapascals environ. Cet étirement de la peau peut être unidirectionnel ou multidirectionnel. Dans d'autres formes de réalisation, ces dispositifs (101, 102, 103, 104, 105) étirent la peau (30) par le biais d'une aspiration ou d'une force normale. L'étirement de la peau (30) permet de maintenir micro-voies (31) ouvertes afin d'améliorer le pénétration d'un agent (p. ex. un médicament) à travers ces dernières. L'étirement retarde en outre la fermeture des micro-voies (31).

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