Slow-release sodium fluoride tablet, method of making, and...

Details Slow-release sodium fluoride tablet, method of making, and... Slow-release sodium fluoride tablet, method of making, and...

A - Human Necessities

61

K

167/292

A61K 9/22 (2006.01) A61K 9/20 (2006.01) A61K 33/16 (2006.01)

Patent

CA 1284110

ABSTRACT A novel use for a slow-release sodium fluoride preparation. Such slow-release sodium preparation is shown to provide a safe but effective level of fluoride in serum, optimal for the treatment of osteoporosis. It minimizes gastrointestinal side effects by limiting the amount of fluoride released in the stomach and it reduces rheumatic complications by avoiding toxic levels of fluoride in serum. The amount of fluoride absorbed is nevertheless sufficient to stimulate bone formation and prevent fractures. Thus, the maintenance of serum fluoride as encompassed in this invention, allows for a safe and effective treatment of osteoporosis.

532639

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