Slow-release sodium fluoride tablet, method of making, and...

A - Human Necessities – 61 – K

Patent

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167/292

A61K 33/16 (2006.01) A61K 9/20 (2006.01)

Patent

CA 1219219

ABSTRACT Sodium fluoride at about 8 to 20 parts, and sugar at about 35 to 45 parts, talc at about 1 to 10 parts, magnesium stearate at about 1 to 5 parts are substantially homogeneously dispersed throughout a wax matrix of carnauba wax at about 35 to 70 parts, at preferred particle sizes, on a weight basis of 100, and the compressed tablet thereof is administered orally to patients in treatment of osteoporosis, and the method includ- ing a required series of selective blending progressively of various of the ingredients at preferred particle sizes, followed by compacting into a dense tablet.

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