Smac peptidomimetics and the uses thereof

Details Smac peptidomimetics and the uses thereof Smac peptidomimetics and the uses thereof

A - Human Necessities

61

K

A61K 38/05 (2006.01) A61K 38/06 (2006.01) C07K 5/062 (2006.01) C07K 5/083 (2006.01)

Patent

CA 2553871

The invention relates to peptidomimetics of Smac which function as inhibitors of Inhibitor of Apoptosis Proteins. The invention also relates to the use of these peptidomimetics for inducing apoptotic cell death and for sensitizing cells to inducers of apoptosis.

L'invention concerne des peptidomimétiques de Smac qui fonctionnent comme des inhibiteurs de l'inhibiteur des protéines de l'apoptose. L'invention concerne également l'utilisation desdits peptidomimétiques pour induire la mort cellulaire apoptotique et pour sensibiliser des cellules à des inducteurs d'apoptose.

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