Small activating rna molecules and methods of use

A - Human Necessities – 61 – K

Patent

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A61K 48/00 (2006.01)

Patent

CA 2604532

The present invention provides compositions, pharmaceutical preparations, kits and methods for increasing expression of a gene product in a cell by contacting the cell with a small activating RNA (saRNA) molecule comprising a ribonucleic strand that is complementary to a non-coding nucleic acid sequence of the gene.

Cette invention concerne des compositions, des préparations pharmaceutiques, des kits et des procédés permettant d'augmenter l'expression d'un produit génique dans une cellule par mise en contact de la cellule avec une molécule ARN à faible activation renfermant un brin ribonucléique qui est complémentaire d'une séquence d'acides nucléiques non codante du gène.

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