A - Human Necessities – 61 – L
Patent
A - Human Necessities
61
L
A61L 27/40 (2006.01) A61F 2/06 (2006.01) A61L 27/18 (2006.01) A61L 27/24 (2006.01) A61L 27/28 (2006.01) A61L 27/36 (2006.01) A61L 27/50 (2006.01) A61L 27/54 (2006.01) A61L 27/58 (2006.01) A61L 33/00 (2006.01) A61L 33/10 (2006.01)
Patent
CA 2327649
A composite graft (10) for a fluid-carrying vessel in a living body, comprising: an inner vessel (12) comprising a biologic collagenic material that has been stabilized, an outer member (14) surrounding at least a segment of the inner vessel (12) and defining an annulus (16) between the inner vessel (12) and the sleeve (14), the outer member (14) comprising a polymeric fabric, and a bioactive compound in said annulus (16), said bioactive compound being carried on a time-release vehicle. The bioactive compound is preferably an occlusion-preventing agent. Alternatively, the sleeve (14) includes the bioactive compound, either on its inner surface or integrally as part of its fibers.
La présente invention concerne une greffe composée (10) pour un vaisseau transportant un fluide dans un organisme vivant, qui comprend les éléments suivants: un vaisseau intérieur (12) renfermant une matière collagène biologique stabilisée; une gaine extérieure (14) en tissu polymère entourant au moins un premier segment du vaisseau intérieur (12) et définissant un espace annulaire (16) entre elle et le vaisseau intérieur (12); et un composé bioactif dans ledit espace annulaire (16) acheminé par un vecteur-retard. Ce composé bioactif est de préférence un agent anti-occlusion. En variante, le composé bioactif peut soit se trouver sur la surface intérieure de la gaine (14), soit être intégré aux fibres de cette dernière.
Chickering Donald Edward
Ranieri John Paul
Sullivan Steven Grant
Ridout & Maybee Llp
Sulzer Innotec Inc.
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