Small molecule immunopotentiators and assays for their...

A - Human Necessities – 61 – K

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Details

A61K 39/39 (2006.01) A61P 11/06 (2006.01) A61P 31/12 (2006.01) A61P 35/00 (2006.01) A61P 37/04 (2006.01) A61P 37/08 (2006.01)

Patent

CA 2571710

The invention provides immunostimulatory compositions comprising a small molecule immuno-potentiator (SMIP) compound and methods of administration thereof. Also provided are methods of administering a SMIP compound in an effective amount to enhance the immune response of a subject to an antigen. Further provided are novel compositions and methods of administering SMIP compounds alone or in combination with another agent for the treatment of cancer, infectious diseases and/or allergies/asthma. In a further aspect, the invention relates generally to methods of screening for small molecule immuno- modulatory compositions.

La présente invention concerne des compositions immunostimulantes comprenant un composé immunopotentialisateur à petites molécules (SMIP) et des méthodes d'administration de ces compositions. Cette invention concerne également des méthodes visant à administrer un composé SMIP en une quantité efficace pour renforcer la réponse immunitaire d'un sujet à un antigène. Cette invention concerne en outre de nouvelles compositions et méthodes d'administration de composés SMIP seuls ou combinés à un autre agent servant au traitement du cancer, de maladies infectieuses et/ou d'allergies/de l'asthme. Dans une variante, cette invention porte d'une manière générale sur des méthodes d'analyse de compositions immunomodulatrices à petites molécules.

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