A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/35 (2006.01) A61K 31/352 (2006.01) A61K 31/404 (2006.01) A61K 31/428 (2006.01) A61K 31/437 (2006.01) A61K 31/496 (2006.01) A61K 31/517 (2006.01) A61K 31/5377 (2006.01)
Patent
CA 2338328
Small molecule inhibitors of Bcl-2 function are used to induce apoptosis of cells which are subject to Bcl-2, which cells are otherwise subject to Bcl-2 mediated blockage of apoptosis. The compounds are useful for treating cancer, autoimmune disorders and viral infection.
L'invention concerne de petites molécules inhibitrices de la fonction Bcl-2 servent à induire l'apoptose de cellules qui sont sujettes à Bcl-2, lesquelles cellules sont autrement sujettes à un blocage de l'apoptose induit par Bcl-2. Les composés selon l'invention conviennent pour le traitement du cancer, de troubles auto-immunes et d'infections virales.
Han Xiaobing
Huang Ziwei
Lui Dongxiang
Wang Jialun
Zhang Zhijia
Gowling Lafleur Henderson Llp
Thomas Jefferson University
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