Small molecule modulators of cytokine activity

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 237/32 (2006.01) A61K 31/502 (2006.01) A61P 35/00 (2006.01) C07D 401/10 (2006.01) C07D 403/10 (2006.01) C07D 403/14 (2006.01)

Patent

CA 2579240

The present invention provides compounds having formula (I) or (II): Formula (I), formula (II) and pharmaceutically acceptable derivatives thereof, wherein m, p, R1, R2, R3 and R4 are as described generally and in classes and subclasses herein, and additionally provides pharmaceutical compositions thereof, and methods for the use thereof for the treatment of any of a number of diseases, disorders or conditions associated with HGF/SF or other cytokine activity.

L'invention concerne des composés de formule (I) ou (II), et des dérivés pharmaceutiquement acceptables de ces composés. Dans lesdites formules, m, p, R1, R2, R3 et R4 sont tels que décrits de manière générale et répartis en classes et sous-classes dans la description. Cette invention se rapporte en outre à des compositions pharmaceutiques de ces composés, et à des procédés d'utilisation desdits composés pour traiter une quelconque maladie ou un quelconque trouble ou état figurant parmi les maladies, troubles et états qui sont associés à l'activité de HGF/SF ou d'une autre cytokine.

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